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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLK All Species: 6.06
Human Site: S689 Identified Species: 12.12
UniProt: Q9H2G2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2G2 NP_055535.2 1235 142695 S689 E K K E I P V S I K K E P E V
Chimpanzee Pan troglodytes XP_508017 1236 142782 S690 E K K E M P V S I K K E P Q V
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 Y89 S P H V V K Y Y G S Y F K N T
Dog Lupus familis XP_544006 1242 143609 P696 K A I P C E M P I K T E L Q V
Cat Felis silvestris
Mouse Mus musculus O54988 1233 141438 P687 K E N A Q K V P V K A E S Q A
Rat Rattus norvegicus O08815 1206 137870 P688 E E N A Q E L P V K A E P Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518991 740 85845 R342 R Q E L R E L R L L Q K E E H
Chicken Gallus gallus XP_421743 1234 142753 I688 P E V S S D K I M K N K L Q D
Frog Xenopus laevis NP_001079164 950 111798 L552 R R Q E L R E L R L L Q K E E
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 D93 G S Y F K N T D L W I V M E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 S271 T E F I D F V S K C L V K E P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 K99 K Y Y G S Y F K H S D L W I V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 20.2 90.1 N.A. 83.6 78.3 N.A. 33.9 72.1 45.5 20.2 N.A. 22.3 N.A. 20.4 N.A.
Protein Similarity: 100 99.6 29.1 94.6 N.A. 89.8 86.3 N.A. 46.3 81.6 59.7 29.6 N.A. 35.6 N.A. 29.2 N.A.
P-Site Identity: 100 86.6 0 26.6 N.A. 20 26.6 N.A. 6.6 6.6 13.3 6.6 N.A. 20 N.A. 6.6 N.A.
P-Site Similarity: 100 100 6.6 46.6 N.A. 46.6 53.3 N.A. 46.6 33.3 40 13.3 N.A. 26.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 0 0 0 0 0 0 17 0 0 0 17 % A
% Cys: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 9 0 9 0 0 9 0 0 0 9 % D
% Glu: 25 34 9 25 0 25 9 0 0 0 0 42 9 42 9 % E
% Phe: 0 0 9 9 0 9 9 0 0 0 0 9 0 0 0 % F
% Gly: 9 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 9 % H
% Ile: 0 0 9 9 9 0 0 9 25 0 9 0 0 9 0 % I
% Lys: 25 17 17 0 9 17 9 9 9 50 17 17 25 0 0 % K
% Leu: 0 0 0 9 9 0 17 9 17 17 17 9 17 0 0 % L
% Met: 0 0 0 0 9 0 9 0 9 0 0 0 9 0 0 % M
% Asn: 0 0 17 0 0 9 0 0 0 0 9 0 0 9 0 % N
% Pro: 9 9 0 9 0 17 0 25 0 0 0 0 25 0 9 % P
% Gln: 0 9 9 0 17 0 0 0 0 0 9 9 0 42 0 % Q
% Arg: 17 9 0 0 9 9 0 9 9 0 0 0 0 0 0 % R
% Ser: 9 9 0 9 17 0 0 25 0 17 0 0 9 0 0 % S
% Thr: 9 0 0 0 0 0 9 0 0 0 9 0 0 0 9 % T
% Val: 0 0 9 9 9 0 34 0 17 0 0 17 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % W
% Tyr: 0 9 17 0 0 9 9 9 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _